NaturalHealing.com

cyboss

About Us

Cyboss 博脉医疗科技. Our Chinese-medicine outpatient service is a group of joint clinics centered on 瑞博中医门诊部. It has had a presence in Beijing, Shenzhen, Guangzhou, Shanghai, and Huzhou, Zhejiang, providing Chinese-medicine care to patients in each place. 瑞博中医门诊部 covers 2,500 square meters and brings together consultation, restorative care, and diet. It has a Chinese-herbal pharmacy and more than 70 treatment beds. We have long followed a rigorous approach to scientific research, carried forward the essence of Chinese medicine, and combined pulse diagnosis, acupuncture, moxibustion, and other Chinese-medicine methods with advanced technology, forming a professional disease program based on data visualization. Over many years, our clinics have made a number of breakthrough research advances in type II diabetes, hypertension, heart failure, brain degeneration, cerebellar atrophy, mental illness, and arterial plaque. More than 40,155 patients have been treated, with good results, and endocrine and metabolic problems have been addressed for 4,819 VIP patients. In 71% of patients with arterial plaque, the plaque was reduced by more than 50% after treatment. The clinical medication-discontinuation rate in type II diabetes was 76%. The clinical recovery rate for triglycerides was 85%. In heart failure, we have made a breakthrough. In several dozen patients, treatment has reduced cardiac enlargement, improved myocardial hypertrophy, and rapidly raised ejection fraction. Every year, critically ill patients with heart failure have come through life-threatening danger after treatment, recovered, and left the intensive-care unit. In cerebellar atrophy, among patients who could not walk independently, whose speech had declined, whose limbs were stiff, and who had mild manic–depressive symptoms, more than ten patients have had significant improvement and progress. Some progressed from being bedridden and unable to turn over by themselves to being able to walk independently. These cases demonstrate the outstanding results of our treatment in conditions such as cerebellar atrophy.

解渤 Ph.D.

Chairman, 重生医药

Authority on Shanghan medicine

Doctor of Chinese Medicine, trained in the United States

In 2015 he returned to China and founded 瑞博健康 , focusing on chronic-disease management. In 2021 he founded 苏州重生医药科技 . He received the Suzhou Leading Talent title (苏州领军人才) and led the development of the world's first innovative drug for arterial plaque. He holds more than 70 invention patents. Bringing together pharmaceutical research teams in China and the United States, he has advanced the development of multiple Class 1.1 innovative drugs in both new Chinese-herbal medicines and biopharmaceuticals. Major breakthroughs have been made in heart failure, coronary heart disease, mental illness, and degenerative brain diseases.

解渤 was born into a family of Chinese-medicine practitioners. He is a descendant of 解德明, known as “圣手先生” at 同义堂 in the late Qing dynasty, and the last disciple of 曾荣修, a master of Shanghan medicine. He has practiced for more than 30 years. He studied the classic formulas and pulse methods of the Shanghan school under 曾荣修, master of the 田曾 lineage (田曾流), and received the core of that lineage’s Shanghan pattern system, which takes pulse study as its basis and its standard: “Where that pulse is present, use that formula.” He set out the mathematical logic of the Hetu and the Luoshu and the foundations of Chinese medicine. He founded the “天道养生” school, bringing herbal medicine, pulse-based formulas, acupuncture, diet, exercise, and daily routine into one practice. Through more than 20 years of theoretical study and clinical work, combined with modern technology, he developed an efficient treatment and management program for metabolic conditions including heart failure, cerebellar atrophy, type 2 diabetes, pulmonary nodules, arterial plaque, and hyperlipidemia.

解涛 Ph.D.

Chief Medical Officer, 太一集团

Authority on Shanghan medicine

Doctor of Chinese Medicine, trained in the United States

He comes from a family of Chinese-medicine practitioners and is a descendant of 解德明, known as “圣手先生” at 同义堂 in the late Qing dynasty, carrying a deep grounding in Chinese medicine and its transmission. He studied under 曾荣修, master of the Shanghan school's 田曾 lineage (田曾流), and studied the essence of Chinese medicine in depth. In his youth he moved with his family to California, continued advanced study, and earned a master's degree and a doctorate. He obtained a California Chinese-medicine practitioner license, operated a Chinese-medicine clinic, and accumulated substantial clinical experience.

He has taken part in studying and developing the “天道养生” theoretical system of Chinese medicine, and works to combine traditional Chinese-medicine knowledge with modern medicine. He has practiced for nearly 30 years, sought out noted physicians, and continued to improve his clinical skill, with substantial experience especially in chronic endocrine disease. In 2017 he returned to China and joined his elder brother, 解渤, in the health enterprise. He became Chief Medical Officer of 太一集团 and took overall charge of its medical work. In 2021 he was invited to see patients at Shenzhen Private Banking of China Construction Bank (深圳建行私人银行), and also served as a specially appointed expert for 平安乐健康.

In clinical practice he has continued to innovate and refine his medicine, and has introduced a number of distinct treatment programs for serious and difficult illnesses. In the diagnosis and treatment of major and chronic conditions, including type 2 diabetes, arterial plaque, heart failure, and pulmonary nodules, he has achieved significant results and brought patients new hope and a new chance.

Facilities

Drug Research & Development

Team

任雪峰, Ph.D.

Tenured professor at the school of medicine and the school of public health of a State University of New York institution
Specially Appointed Professor at Fudan University School of Medicine (中国复旦大学医学院,), and a recipient of the Shanghai Thousand Talents Program at Fudan University (上海千人计划).
Short-term work at the U.S. FDA and GeneTech Inc.
He has taken part in founding several biomedical technology companies in China and the United States, including, in the United States, Sandalwood Biotech. Ltd. and Quatuor Medical Diagnostics and Technologies, LLC, and, in China, 广东众尔健生物科技有限公司.
There he has led development of GMDTC, a drug intended to reduce toxicity and increase efficacy in tumor chemotherapy. The IND submission has been completed, and the program is about to enter clinical research.

程震 博士

美国 University of Missouri-Columbia 博士, 哈佛医学院生物化学/放射化学博士后研究员。
中科院药物研究所分子影像中心主任,上海科技大学生物医学工程学院特聘教授。
曾任美国斯坦福大学分子影像中心肿瘤分子影像化学实验室主任, 斯坦福大学医学院分子影像中心、克莱瑞-斯坦福癌症早期检测研究中心、 斯坦福癌症研究所、 放射科及 BioX 中心副教授

专家顾问团队
中药与西药对比优势明显
中药的优势

单一化合物——原则上是瞄准单一问题,单一靶点,

Research Background

动脉斑块项目背景

动脉粥样斑块形成和硬化(atherosclerosis, AS)是中风、缺血性心脏病,以及外周血管病的主要原因。
动脉粥样斑块形成和硬化机制非常复杂,牵扯的因素非常多,包括脂质代谢障碍,心脏平滑肌的损伤,胶原纤维增生,炎性因子聚集等等。因此斑块形成和硬化是一个多机制,长期病变发展的结果。

脑梗
(缺血性中风)

冠心病,心梗
(缺血性心脏病)

下肢动脉栓塞

——多靶点, 多机制。化药, 生物药研发尚未突破

——软斑块建议吃他汀药物(降脂药),狭窄大于50%建议吃他汀+阿司匹林,更严重的狭窄支架或外科手术

——目前临床上应用的降血脂类化药品种较多,尽管机理不同, 但主要都是通过直接作用于脂肪本身

——化学合成降血脂药物需要长期服用;停药后血脂反弹几率非常高;长期服用大大增加毒副作用产生几率

——临床上降血脂药对于预防动脉粥样硬化性心脑血管疾病疾病造成的死亡,几无作用

Research Results

动脉斑块治疗药物:CS-001发明专利知识产权

已在中国、美国、欧盟、韩国、俄罗斯、日本、新加坡、中国台湾获得授权。

动物实验 降脂疗效统计

通过给药前和给药后的数据对比,本发明中药组合物在动物实验中,

动脉斑块治疗药物动物实验(消减斑块/改善血管及周围炎性环境,效果显著)

Treatment Areas

动脉斑块的相关检查

血脂:由胆固醇、甘油三酯、磷脂和非游离脂肪酸共同组成。
高密度脂蛋白-胆固醇(HDL-C):对心血管有保护作用,可将有害的胆固醇从血管内壁带到肝脏,经吸收和有效利用,然后排出体外。

低密度脂蛋白-胆固醇(LDL-C):一旦高血压、糖尿病、吸烟等因素使血管内皮有漏洞,他们就会钻到动脉的内皮下面,形成动脉粥样硬化斑块,最终导致心脑血管疾病。

血糖:血糖与血脂异常息息相关,尤其是血糖控制不好的糖尿病患者,血管疾病问题尤其严重。

血常规:尤其指红细胞、血小板等的数量、压积、聚集指数,血沉、血浆粘度等,有较大影响。
凝血四项:凝血酶原时间,纤维蛋白原含量,凝血活酶时间等。

动脉斑块主要治疗药物

◈ 他汀类

◈ 抗凝类

◈ 贝特类、 烟酸类

◈ 深度治疗

英国顶级心脏专家:他汀没用

阿西姆·马尔霍特拉 (Aseem Malhotra): 英国工党副领袖、 最具影响力的心脏病专家

Dr Malhotra谴责所谓的医学权威对总胆固醇水平的痴迷,他说这导致了数百万人,过度服用他汀类药物,并转移了真凶的注意力。

他质疑他汀类药物的价值,认为它对任何人都没 有好处,就在上年,他还写了一本书a statin free life《没有他汀的生活:治疗心脏病的革命 性计划》。

动脉粥样硬化才是真正的杀手

导致胆固醇在动脉壁内沉积,和随后的斑块形成 (动脉粥样硬化)的炎症过程,接近于“丘疹” 的形成过程。

ESC:阿司匹林的预防作用并不足以抵消其带来的副作用

欧洲心脏病学会年会(简称ESC,每年一度的ESC是全球规模最大、最具影响力的国际心血管学术会议)上,哈佛大学和牛津大学的临床研究报告都显示,对于尚未出现心血管疾病的人来说,阿司匹林的预防作用并不足以抵消其带来的副作用。

牛津大学的实验针对的是糖尿病患者,这是心血管疾病的高危群体。最终实验显示,在超过 7 年的实验时间里,阿司匹林仅将严重心血管疾病的风险降低了12%,但是却将发生大出血概率提高了 29%。

FDA 称,对未患过心血管疾病的人来说,每日服用阿司匹林所具有的早期预防作用并不明显,反而会带来大脑或胃部出血的副作用。

150万个/年,普通支架平均约3万

后续吃一辈子药:抗凝药波立维、阿司匹林

开胸手术

后期还会堵塞

大手术

后续吃一辈子药:抗凝药波立维、阿司匹林、抗免疫

Treatment Approach

通过实验研究发现,动脉斑块治疗中药通过干预IL17A/NFKB炎症调控信号通路,可显著改善APOE-/-小鼠血清及主动脉斑块内炎症因子表达水平,从而改善AS斑块的形成的微环境及稳定性。

与正常组相比,模型组小鼠血清中IL-6、IL1β、IL17A的含量显著增加(P<0.01),与模型组比较,动脉斑块治疗中药组小鼠血清中IL-6、IL1β、IL17A的含量降低,高剂量组差异表达更加显著(P<0.01),表明动脉斑块治疗中药可减轻AS小鼠血清炎症水平。与正常组比,模型组小鼠主动脉斑块内的IL17A/NFKB炎症通路蛋白表达显著增加(P<0.01),与模型组比较,动脉斑块治疗中药组小鼠主动脉斑块内的IL17A/NFKB炎症通路蛋白表达水平减少,高剂量组差异表达更加显著(P<0.01),表明动脉斑块治疗中药可以减少IL17A/NFKB炎症通路蛋白表达,减轻炎症对血管的损伤。

血管硬化与血液粘稠

西方医学发现,血液成分是造成血管疾病的核心原因!
血管硬化是因为血液粘稠,而造成血液粘稠的原因是 什么? 是血液成分发生了错误的改变!
血液粘稠度在现代医学生化指标中的主要指标里,有30多个指标:
· 血糖指标:空腹血糖、糖化血红蛋白、空腹胰岛素、C肽等
· 血脂指标:高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘 油三 脂、载脂蛋白等
· 血常规:与血小板相关的指标、与红血球相关的指标等血液粘度相关指标
如果这些指标都正常, 那么血液是否没有粘稠呢?
答案是: 还是有几率粘稠!!!

Case Studies

张先生,52岁
2024年4月冠脉增强CT显示:左前降支近段及中段多发混合斑块,管腔最狭窄约60%;中间支近段局限混合斑块伴轻度狭窄。
右冠近中段混合斑块,管腔狭窄约40%

期间服用约2个月的动脉斑块治疗药物
左前降支近段多个混合斑块,管腔最窄约35%;中段非钙化斑块伴管腔狭窄约40%;中间支小钙化伴管腔轻度狭窄考虑。
(之前两处均狭窄60%)
右冠近段管壁毛糙增厚伴非钙化斑块,管腔轻度狭窄考虑。
(之前狭窄40%)

解决血管堵塞问题

林女士,70岁
居住在澳大利亚
堵塞超过90%的颈动脉斑块 和脑部动脉斑块,经过6个 月的中药治疗,治疗期血 管堵塞都转为轻度

解决血管堵塞问题——100%消失

李先生|51岁

饮酒多,双侧颈总动脉动脉硬化斑块形成,高血脂,糖尿病,高血压。
治疗后,降脂药停用,血脂、血糖、血压恢复正常。
2019年6月复查,颈动脉斑块消失。

解决血管堵塞问题——缩小70.8%

李女士,64岁 检查有多发颈动脉斑块,左侧颈总动脉分叉处13.62.5mm,4.81.6mm的两个斑块,两个月治疗,复查斑块已经缩小为只有一个5.8*2.1mm,总胆固醇也降到了正常。

解决血管堵塞问题——缩小81.5%

李女士,65岁 检查有多发颈动脉斑块,4个较大斑块:12.12.6,10.22,101.9,5.62mm。断续服用中药复查治疗效果见:最大的两个斑块已经是3.92.5,2.62.1mm,明显缩小甚至消失。

解决血管堵塞问题——缩小70%

郑先生,49岁 治疗前斑块尺寸1.15*0.2cm,3个月治疗后复查:斑块尺寸0.5*0.14cm

解决血管堵塞问题——缩小100%

张先生,36岁

2020年5月22日彩超示: 斑块9.2*2.2mm
2020年10月来我机构治疗糖尿病, 仅经过9次问诊开方
2021年6月24日彩超示: 斑块完全消失, 血糖也全部在正常范围之内

糖尿病

心衰

动脉斑块

房颤

帕金森

心肌肥大性心脏病

脑溢血

其他

Affiliated Clinics

浙江湖州瑞博同義堂中医门诊部(浙江医疗基地)

浙江省湖州市南太湖度假区梅州路323号

+86-0572-2201880

Sunnyvale Clinic

1287 Hammerwood Ave, Sunnyvale CA 94089

Tel: 408-732-8328

同义堂网址:https://ty.naturalhealing.com

返回顶部